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Article

The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis.

The Journal of biological chemistry - 6 Sept 2002

Schwientek Tilo, Keck Birgit, Levery Steven B, Jensen Mads A, Pedersen Johannes W, Wandall Hans H, Stroud Mark, Cohen Stephen M, Amado Margarida, Clausen Henrik

Abstract excerpt

The Drosophila genes fringe and brainiac exhibit sequence similarities to glycosyltransferases. Drosophila and mammalian fringe homologs encode UDP-N-acetylglucosamine:fucose-O-Ser beta1,3-N-acetylglucosaminyltransferases that modulate the function of Notch family receptors. The biological function of brainiac is less well understood. brainiac is a member of a large homologous mammalian beta3-glycosyltransferase...

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PMID: 12130651
DOI: 10.1074/jbc.M206213200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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