Article
SNP-SNP Interaction between TLR4 and MyD88 in Susceptibility to Coronary Artery Disease in the Chinese Han Population.
International journal of environmental research and public health - 4 Mar 2016
Sun Dandan, Sun Liping, Xu Qian, Gong Yuehua, Wang Honghu, Yang Jun, Yuan Yuan
Abstract excerpt
The toll-like receptor 4 (TLR4)-myeloid differentiation factor 88 (MyD88)-dependent signaling pathway plays a role in the initiation and progression of coronary artery disease (CAD). We investigated SNP-SNP interactions between the TLR4 and MyD88 genes in CAD susceptibility and assessed whether the effects of such interactions were modified by confounding risk factors (hyperglycemia, hyperlipidemia and...
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