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Article

Promoter Polymorphism of Toll-Like Receptor 4 is Associated with a Decreased Risk of Coronary Artery Disease: A Case-Control Study in the Chinese Han Population.

Medical science monitor : international medical journal of experimental and clinical research - 16 Jan 2017

Sun Dandan, Sun Liping, Xu Qian, Wang Honghu, Yang Jun, Yuan Yuan

Abstract excerpt

BACKGROUND Coronary artery disease (CAD) is considered a chronic inflammatory disease of the blood vessels. Toll-like receptor 4 (TLR4) is a transmembrane receptor involved in inflammatory reactions. The aim of this study was to determine the association between polymorphisms in the promoter region and 3'-untranslated region (3'-UTR) of TLR4, and the associated CAD risk. MATERIAL AND METHODS This study enrolled...

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Source

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Identifiers

PMID: 28092654
DOI: 10.12659/msm.899587
PMCID: PMC5266207

Genes

CAD
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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