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Article

Association of TLR and TREM-1 gene polymorphisms with risk of coronary artery disease in a Russian population.

Gene - 15 Oct 2014

Golovkin Alexey S, Ponasenko Anastasia V, Khutornaya Maria V, Kutikhin Anton G, Salakhov Ramil R, Yuzhalin Arseniy E, Zhidkova Irina I, Barbarash Olga L, Barbarash Leonid S

Abstract excerpt

Atherosclerosis, manifesting itself as acute coronary syndrome, stroke, and peripheral arterial diseases, is a chronic progressive inflammatory disease which is driven by responses of both innate and adaptive immunity. Toll-like receptors (TLRs) and Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) are important effectors of the innate immune system, and polymorphisms within genes encoding them may...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25128583
DOI: 10.1016/j.gene.2014.08.022

Genes

CAD
TLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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