Article
TLR signalling and association of TLR polymorphism with cardiovascular diseases.
Vascular pharmacology - 1 Dec 2016
Sharma Swati, Garg Iti, Ashraf Mohammad Z
Abstract excerpt
Toll-Like receptors (TLRs) are the primary receptors of innate immunity. Considerable evidences have shown that innate immune defence interaction with pro-inflammatory pathways could be through TLRs that in turn leads to development of inflammatory diseases. These TLRs are present on various tissues and cells of cardiovascular system. Previous studies involving SNPs analysis of TLRs demonstrated that TLRs are...
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