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Article

Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous gene.

Retrovirology - 4 Nov 2008

De Marco Alex, Biancotto Chiara, Knezevich Anna, Maiuri Paolo, Vardabasso Chiara, Marcello Alessandro

Abstract excerpt

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) favors integration in active genes of host chromatin. It is believed that transcriptional interference of the viral promoter over the endogenous gene or vice versa might occur with implications in HIV-1 post-integrative transcriptional latency. RESULTS: In this work a cell line has been transduced with a HIV-based vector and selected for Tat-inducible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18983639
DOI: 10.1186/1742-4690-5-98
PMCID: PMC2586024

Genes

HMBOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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