Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 Promoter

1 May 1998

Abstract excerpt

The regulation of human immunodeficiency virus type 1 (HIV-1) gene expression involves a complex interplay between cellular transcription factors, chromatin-associated proviral DNA, and the virus-encoded transactivator protein, Tat. Here we show that Tat transactivates the integrated HIV-1 long terminal repeat (LTR), even in the absence of detectable basal promoter activity, and this transcriptional activation is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9566873
DOI: 10.1128/mcb.18.5.2535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 PromoterPMID 9566873Read ↗

Chromatin Remodeling and Modification during HIV-1 Tat-activated TranscriptionSemantic proximity Read ↗

cis-Acting Sequences Located Downstream of the Human Immunodeficiency Virus Type 1 Promoter Affect Its Chromatin Structure and Transcriptional ActivitySemantic proximity Read ↗

Activation of Integrated Provirus Requires Histone AcetyltransferaseSemantic proximity Read ↗

Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review).Semantic proximity Read ↗

Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation.Semantic proximity Read ↗

Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65Semantic proximity Read ↗

Regulation of HIV‐1 gene expressionSemantic proximity Read ↗

Negative Elongation Factor NELF Represses Human Immunodeficiency Virus Transcription by Pausing the RNA Polymerase II ComplexSemantic proximity Read ↗

The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcriptionSemantic proximity Read ↗

The SWI/SNF Chromatin-remodeling Complex Is a Cofactor for Tat Transactivation of the HIV PromoterSemantic proximity Read ↗

Transcriptional Repression of Human Immunodeficiency Virus Type 1 by AP-4Semantic proximity Read ↗

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.