Article
Analysis of a functional serotonin transporter promoter polymorphism in psoriasis vulgaris.
Archives of dermatological research - 1 Jul 2009
Mössner Rotraut, Stiens Gerthild, König Inke R, Schmidt Diane, Platzer Anja, Krüger Ullrich, Reich Kristian
Abstract excerpt
Serotonin is a monoamine acting as a neuromediator in the central and peripheral nervous system. Recently, serotonin has also been shown to influence T- and B-cell function. The serotonin transporter is central in the regulation of the serotonergic system and widely expressed on cells of the immune system. A functional length polymorphism in the promoter of the serotonin transporter gene (5-HTTLPR) has been...
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