Article
Serotonin transporter gene polymorphisms in patients with unipolar or bipolar depression.
Neuroscience letters - 23 Oct 1998
Bellivier F, Henry C, Szöke A, Schürhoff F, Nosten-Bertrand M, Feingold J, Launay J M, Leboyer M, Laplanche J L
Abstract excerpt
To explore the involvement of serotonin transporter (5HTT) in mood disorder, we studied two polymorphisms of the 5HTT gene (a variable number of tandem repeats in the second intron (VNTR) and a 44 bp insertion/deletion in the 5HTT linked polymorphic region (5-HTTLPR)) in a sample of unipolar and...
Topics
- Adult
- Alleles
- Bipolar Disorder
- Carrier Proteins
- DNA Transposable Elements
- Depressive Disorder
- Female
- Gene Deletion
- Gene Frequency
- Genotype
- Homozygote
- Humans
- Introns
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Nerve Tissue Proteins
- Polymorphism, Genetic