Article
Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2008
Vieira Alexandre R, McHenry Toby G, Daack-Hirsch Sandra, Murray Jeffrey C, Marazita Mary L
Abstract excerpt
PURPOSE: We revisited 42 families with two or more cleft-affected siblings who participated in previous studies. Complete dental information was collected to test the hypothesis that dental anomalies are part of the cleft phenotype spectrum, and can provide new opportunities for identification of cleft susceptibility genes. METHODS: Genotypes from 1489 single nucleotide polymorphism markers located in 150...
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