Article
The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development.
Developmental biology - 1 Jan 2009
Kurpios Natasza A, MacNeil Lesley, Shepherd Trevor G, Gludish David W, Giacomelli Andrew O, Hassell John A
Abstract excerpt
The Pea3 Ets transcription factor is overexpressed in breast tumors suggesting that it plays a role in mammary oncogenesis. However, the normal biological function of Pea3 in the mammary gland is not known. Here we report that Pea3 was expressed in the epithelium of the mouse mammary anlagen comm...
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