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Article

The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development.

Developmental biology - 1 Jan 2009

Kurpios Natasza A, MacNeil Lesley, Shepherd Trevor G, Gludish David W, Giacomelli Andrew O, Hassell John A

Abstract excerpt

The Pea3 Ets transcription factor is overexpressed in breast tumors suggesting that it plays a role in mammary oncogenesis. However, the normal biological function of Pea3 in the mammary gland is not known. Here we report that Pea3 was expressed in the epithelium of the mouse mammary anlagen commensurate with their genesis, and at later times in the nipple and mammary ducts of female embryos. In adult mice Pea3...

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Identifiers

PMID: 18977342
DOI: 10.1016/j.ydbio.2008.09.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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