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Article

Early lineage segregation of multipotent embryonic mammary gland progenitors.

Nature cell biology - 1 Jun 2018

Wuidart Aline, Sifrim Alejandro, Fioramonti Marco, Matsumura Shigeru, Brisebarre Audrey, Brown Daniel, Centonze Alessia, Dannau Anne, Dubois Christine, Van Keymeulen Alexandra, Voet Thierry, Blanpain Cédric

Abstract excerpt

The mammary gland is composed of basal cells and luminal cells. It is generally believed that the mammary gland arises from embryonic multipotent progenitors, but it remains unclear when lineage restriction occurs and what mechanisms are responsible for the switch from multipotency to unipotency during its morphogenesis. Here, we perform multicolour lineage tracing and assess the fate of single progenitors, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammary Glands, Animal

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Identifiers

PMID: 29784918
DOI: 10.1038/s41556-018-0095-2
PMCID: PMC5985933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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