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Article

Autophagy and insulin/TOR signaling in Caenorhabditis elegans pcm-1 protein repair mutants.

Autophagy - 1 Jan 2000

Gomez Tara A, Clarke Steven G

Abstract excerpt

Biological responses due to nutrient deprivation in the nematode Caenorhabditis elegans, including L1 diapause and autophagy during dauer formation, can be mediated through the linked DAF-2/insulin/IGF receptor and target-of-rapamycin (TOR) kinase pathways. Here we discuss how altered insulin/TOR signaling may underlie the previously reported phenotypes of worms with a null mutation in the pcm-1 gene that results...

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Identifiers

PMID: 17404495
DOI: 10.4161/auto.4143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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