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Article

N-lobe dynamics of myosin light chain dictates its mode of interaction with myosin V IQ1.

Biochemistry - 25 Nov 2008

Amata Irene, Gallo Mariana, Pennestri Matteo, Paci Maurizio, Ragnini-Wilson Antonella, Cicero Daniel O

Abstract excerpt

Myosin V motors regulate secretion and cell division in eukaryotes. How MyoV activity is differentially regulated by essential and calmodulin light chain binding remains unclear. We have used NMR spectroscopy to compare the dynamic behavior of Mlc1p, a budding yeast essential light chain, with that of the Xenopus laevis calmodulin. Both proteins have a similar structure and bind similar target proteins but differ...

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PMID: 18975975
DOI: 10.1021/bi801178t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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