Dissecting the molecular assembly of the Toxoplasma gondii MyoA motility complex

Abstract excerpt

Apicomplexan parasites such as Toxoplasma gondii rely on a unique form of locomotion known as gliding motility. Generating the mechanical forces to support motility are divergent class XIV myosins (MyoA) coordinated by accessory proteins known as light chains. Although the importance of the MyoA–light chain complex is well-established, the detailed mechanisms governing its assembly and regulation are relatively...

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