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Article

Structural basis of cargo recognitions for class V myosins.

Proceedings of the National Academy of Sciences of the United States of America - 9 Jul 2013

Wei Zhiyi, Liu Xiaotian, Yu Cong, Zhang Mingjie

Abstract excerpt

Class V myosins (MyoV), the most studied unconventional myosins, recognize numerous cargos mainly via the motor's globular tail domain (GTD). Little is known regarding how MyoV-GTD recognizes such a diverse array of cargos specifically. Here, we solved the crystal structures of MyoVa-GTD in its apo-form and in complex with two distinct cargos, melanophilin and Rab interacting lysosomal protein-like 2. The...

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Identifiers

PMID: 23798443
DOI: 10.1073/pnas.1306768110
PMCID: PMC3710815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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