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Article

Structure of the small Dictyostelium discoideum myosin light chain MlcB provides insights into MyoB IQ motif recognition.

The Journal of biological chemistry - 13 Jun 2014

Liburd Janine, Chitayat Seth, Crawley Scott W, Munro Kim, Miller Emily, Denis Chris M, Spencer Holly L, Côté Graham P, Smith Steven P

Abstract excerpt

Dictyostelium discoideum MyoB is a class I myosin involved in the formation and retraction of membrane projections, cortical tension generation, membrane recycling, and phagosome maturation. The MyoB-specific, single-lobe EF-hand light chain MlcB binds the sole IQ motif of MyoB with submicromolar affinity in the absence and presence of Ca(2+). However, the structural features of this novel myosin light chain and...

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Identifiers

PMID: 24790102
DOI: 10.1074/jbc.M113.536532
PMCID: PMC4059145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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