Article
ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2008
Talmud Philippa J, Smart Melissa, Presswood Edward, Cooper Jackie A, Nicaud Viviane, Drenos Fotios, Palmen Jutta, Marmot Michael G, Boekholdt S Matthijs, Wareham Nicholas J, Khaw Kay-Tee, Kumari Meena, Humphries Steve E
Abstract excerpt
BACKGROUND: Angiopoietin-like 4 is a dual-function protein: an inhibitor of LPL, influencing plasma triglycerides (TGs), with angiogenic properties. We examined the association of common ANGPTL4 variants with CHD traits and risk in 5 studies (13,527 individuals). METHODS AND RESULTS: The effects...
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