Article
Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events.
Current opinion in lipidology - 1 Feb 2010
Miida Takashi, Hirayama Satoshi
Abstract excerpt
PURPOSE OF REVIEW: Angiopoietin-like proteins (Angptls) comprise a family of secreted glycoproteins with high homology to angiopoietins which are important regulators of angiogenesis. Angptl3 and Angptl4 inhibit lipoprotein lipase in mice. This article reviews recent human studies on Angptls and their effects on lipoprotein profiles and cardiovascular disease. RECENT FINDINGS: Population-based studies have...
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