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Article

Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.

Proceedings of the National Academy of Sciences of the United States of America - 4 Nov 2008

Iwai Sosuke, Uyeda Taro Q P

Abstract excerpt

Many proteins have been shown to undergo conformational changes in response to externally applied force in vitro, but whether the force-induced protein conformational changes occur in vivo remains unclear. To reveal the force-induced conformational changes, or strains, within proteins in living cells, we have developed a genetically encoded fluorescent "strain sensor," by combining the proximity imaging (PRIM)...

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Identifiers

PMID: 18971336
DOI: 10.1073/pnas.0805513105
PMCID: PMC2579347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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