Article
Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin.
The Journal of biological chemistry - 18 Feb 2005
Fujita-Becker Setsuko, Dürrwang Ulrike, Erent Muriel, Clark Richard J, Geeves Michael A, Manstein Dietmar J
Abstract excerpt
Class I myosins are single-headed motor proteins implicated in various motile processes including organelle translocation, ion channel gating, and cytoskeleton reorganization. Dictyostelium discoideum myosin-ID belongs to subclass 1alpha, whose members are thought to be tuned for rapid sliding. The direct analysis of myosin-ID motor activity is made possible by the production of single polypeptide constructs...
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