Article
[The role of polymerase protein genes of influenza A virus in the transition from the early to late stage of replication].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 May 1991
Gubareva L V, Markushin S G, Varich N L, Kaverin N V
Abstract excerpt
Regulation of influenza virus RNA replication was studied with the use of A/FPV/Rostock/34 strain ts-mutants. Mutants C44, C15, C45 possessing the ts-defects in the PB2, PB1 and PA genes respectively were used for the infection of chick embryo cultured cells and H-uridine-labelled nucleocapsid-associated RNA was analysed in polyacrylamide gel electrophoresis to assess the kinetics of vRNA synthesis. A typical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
