Article
[Persistent influenza virus infection. Molecular genetic characteristics of ts mutants selected during persistence].
Voprosy virusologii - 1 Jan 2000
Medvedeva M N, Medvedeva T E, Aron R A, Iukhnova L G, Simanovskaia V K
Abstract excerpt
Properties of ts mutants isolated from systems of persistent influenza infection formed in MDCK cell culture by A/Victoria/35/72 virus were studied. The ts mutants isolated at later intervals of persistent infection (158 days) were characterized by thermolability of hemagglutinin and neuraminidas...
Topics
- Animals
- Defective Viruses
- Genes, Viral
- Hemagglutinins, Viral
- Influenza A virus
- Mutation
- Neuraminidase
- Orthomyxoviridae Infections
- Peptides
- Recombination, Genetic
- Selection, Genetic
- Temperature
- Virus Cultivation
