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Article

Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia.

PloS one - 1 Jan 2013

Douvaras Panagiotis, Mort Richard L, Edwards Dominic, Ramaesh Kanna, Dhillon Baljean, Morley Steven D, Hill Robert E, West John D

Abstract excerpt

We aimed to test previous predictions that limbal epithelial stem cells (LESCs) are quantitatively deficient or qualitatively defective in Pax6(+/-) mice and decline with age in wild-type (WT) mice. Consistent with previous studies, corneal epithelial stripe patterns coarsened with age in WT mosa...

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Source

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Identifiers

PMID: 23967157
DOI: 10.1371/journal.pone.0071117
PMCID: PMC3742784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23967157-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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