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Article

The C677T polymorphism in MTHFR is not associated with migraine in Portugal.

Disease markers - 1 Jan 2008

Ferro Anabela, Castro Maria-José, Lemos Carolina, Santos Mónica, Sousa Alda, Pereira-Monteiro José, Sequeiros Jorge, Maciel Patrícia

Abstract excerpt

Migraine is a debilitating disorder affecting a large proportion of the population. The effect of methylenetetrahydrofolate reductase (GeneID: 4524) polymorphisms in migraine etiology and development has been a theme of great interest. Several populations were evaluated with contradictory results. In this case-control study, we investigated the effect of the C677T polymorphism in MTHFR, as a genetic risk factor...

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Source

Open in PubMed Open full text

Identifiers

PMID: 18957721
DOI: 10.1155/2008/178679
PMCID: PMC3827821

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The C677T polymorphism in MTHFR is not associated with migraine in Portugal.PMID 18957721Read ↗

MTHFR T677 Homozygosis Influences the Presence of Aura in MigraineursSemantic proximity Read ↗

Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.Semantic proximity Read ↗

Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.Semantic proximity Read ↗

MTHFR C677T polymorphism and migraine risk: a meta-analysis.Semantic proximity Read ↗

Association of MTHFR gene polymorphisms with migraine in North Indian population.Semantic proximity Read ↗

Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphism (MTHFR C677T) and headache in children: a retrospective study from a tertiary level outpatient service.Semantic proximity Read ↗

The role of the MTHFR gene in migraine.Semantic proximity Read ↗

Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis.Semantic proximity Read ↗

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