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Article

MTHFR T677 Homozygosis Influences the Presence of Aura in Migraineurs

20 May 2004

Abstract excerpt

It has been suggested that folate metabolism could be involved in migraine pathogenesis. We analysed the 5',10'-methylenetetrahydrofolate reductase (MTHFR) genotypic distribution in a large migraine sample. We genotyped 230 migraine patients (152 migraine without aura (MO) and 78 migraine with aura (MA)) and 204 nonheadache controls. The incidence of TT homozygosis for migraine in general (12%), MO (9%) and MA...

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Identifiers

PMID: 15154859
DOI: 10.1111/j.1468-2982.2004.00692.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR T677 Homozygosis Influences the Presence of Aura in MigraineursPMID 15154859Read ↗

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.Semantic proximity Read ↗

Migraine and MTHFR C677T genotype in a population-based sample.Semantic proximity Read ↗

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Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.Semantic proximity Read ↗

Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.Semantic proximity Read ↗

Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

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The C677T polymorphism in MTHFR is not associated with migraine in Portugal.Semantic proximity Read ↗

The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.Semantic proximity Read ↗

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