Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of the MTHFR gene in migraine.

Headache - 1 Mar 2012

Stuart Shani, Cox Hannah C, Lea Rod A, Griffiths Lyn R

Abstract excerpt

Migraine is a common neurological disorder and is characterized by debilitating head pain and an assortment of additional symptoms which can include nausea, emesis, photophobia, phonophobia, and occasionally, visual sensory disturbances. A number of genes have been implicated in the pathogenesis of this disease, including genes involved in regulating the vascular system. Of particular importance are the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polymorphism, Single Nucleotide
Share to Vitamins
Share to Australia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to MTHFR gene

Share to Genetic Predisposition to Disease

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Migraine Disorders

Source

Identifiers

PMID: 22375693
DOI: 10.1111/j.1526-4610.2012.02106.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of the MTHFR gene in migraine.PMID 22375693Read ↗

Targeting MTHFR for the treatment of migrainesSemantic proximity Read ↗

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.Semantic proximity Read ↗

Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.Semantic proximity Read ↗

Association study of MTHFD1 coding polymorphisms R134K and R653Q with migraine susceptibility.Semantic proximity Read ↗

Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

Association of MTHFR gene polymorphisms with migraine in North Indian population.Semantic proximity Read ↗

Migraine and MTHFR C677T genotype in a population-based sample.Semantic proximity Read ↗

Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.Semantic proximity Read ↗

Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.Semantic proximity Read ↗

Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.Semantic proximity Read ↗

MTHFR T677 Homozygosis Influences the Presence of Aura in MigraineursSemantic proximity Read ↗

A possible role for mitochondrial dysfunction in migraine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.