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Article

The role of the MTHFR gene in migraine.

Headache - 1 Mar 2012

Stuart Shani, Cox Hannah C, Lea Rod A, Griffiths Lyn R

Abstract excerpt

Migraine is a common neurological disorder and is characterized by debilitating head pain and an assortment of additional symptoms which can include nausea, emesis, photophobia, phonophobia, and occasionally, visual sensory disturbances. A number of genes have been implicated in the pathogenesis...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22375693
DOI: 10.1111/j.1526-4610.2012.02106.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22375693-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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The role of the MTHFR gene in migraine.PMID 22375693Read ↗

Targeting MTHFR for the treatment of migrainesSemantic proximity Read ↗

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Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

Association of MTHFR gene polymorphisms with migraine in North Indian population.Semantic proximity Read ↗

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Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.Semantic proximity Read ↗

Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.Semantic proximity Read ↗

MTHFR T677 Homozygosis Influences the Presence of Aura in MigraineursSemantic proximity Read ↗

A possible role for mitochondrial dysfunction in migraine.Semantic proximity Read ↗

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