Article
Dark brown is the more virulent of the switch phenotypes of Candida glabrata.
Microbiology (Reading, England) - 1 Nov 2008
Srikantha Thyagarajan, Daniels Karla J, Wu Wei, Lockhart Shawn R, Yi Song, Sahni Nidhi, Ma Ning, Soll David R
Abstract excerpt
Candida glabrata undergoes reversible, high-frequency core switching between phenotypes that include dark brown (DB), light brown (LB) and white (Wh). These phenotypes in turn can switch to the irregular wrinkle (IWr) phenotype. Natural isolates, however, express predominantly the DB phenotype, leading to the hypothesis that it has a colonization advantage over the other switch phenotypes. Using the mouse model...
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