Article
Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer.
Genetics and molecular research : GMR - 22 Feb 2016
Almeida B C, Kleine J P F O, Camargo-Kosugi C M, Lisboa M R, França C N, França J P, Silva I D C G
Abstract excerpt
The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants; the cancer-free control subjects were 26-72...
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