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Article

Evolutionary footprints of nucleosome positions in yeast.

Trends in genetics : TIG - 1 Dec 2008

Washietl Stefan, Machné Rainer, Goldman Nick

Abstract excerpt

Using genome-wide maps of nucleosome positions in yeast, we have analyzed the influence of chromatin structure on the molecular evolution of genomic DNA. We have observed, on average, 10-15% lower substitution rates in linker regions than in nucleosomal DNA. This widespread local rate heterogeneity represents an evolutionary footprint of nucleosome positions and reveals that nucleosome organization is a genomic...

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PMID: 18951646
DOI: 10.1016/j.tig.2008.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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