Article
Nucleosome positioning stability is a significant modulator of germline mutation rate variation across the human genome
2018-12-13
Abstract excerpt
Understanding the patterns and genesis of germline de novo mutations is important for studying genome evolution and human diseases. Nucleosome organization is suggested to be a contributing factor to mutation rate variation across the genome. However, the small number of published de novo mutations and the low resolution of earlier nucleosome maps limited our understanding of how nucleosome organization affects...
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Identifiers and source
- Literature Corpus work
- bdd0868c-dcd5-5f6b-ae76-3ca0c2b67065
- DOI
- 10.1101/494914