Article
The impact of the nucleosome code on protein-coding sequence evolution in yeast.
PLoS genetics - 1 Nov 2008
Warnecke Tobias, Batada Nizar N, Hurst Laurence D
Abstract excerpt
Coding sequence evolution was once thought to be the result of selection on optimal protein function alone. Selection can, however, also act at the RNA level, for example, to facilitate rapid translation or ensure correct splicing. Here, we ask whether the way DNA works also imposes constraints on coding sequence evolution. We identify nucleosome positioning as a likely candidate to set up such a DNA-level...
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