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Article

Relationship between soluble MICA and the MICA A5.1 homozygous genotype in patients with oral squamous cell carcinoma.

Clinical immunology (Orlando, Fla.) - 1 Mar 2009

Tamaki Shigehiro, Kawakami Masayoshi, Yamanaka Yasutsugu, Shimomura Hiroyuki, Imai Yuichiro, Ishida Jun-ichi, Yamamoto Kazuhiko, Ishitani Akiko, Hatake Katsuhiko, Kirita Tadaaki

Abstract excerpt

NK and cytotoxic T cells play an important role in the elimination of virus-infected and tumor cells through NKG2D activating receptors, which can promote the lysis of target cells by binding to the major histocompatibility complex class I-related chain A (MICA) proteins. Polymorphisms in MICA may influence its binding to the NKG2D. The soluble form of MICA is released from the surface of tumor cells of...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Histocompatibility Antigens Class I

Share to Mouth Neoplasms

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Source

Identifiers

PMID: 18951065
DOI: 10.1016/j.clim.2008.09.004

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Relationship between soluble MICA and the MICA A5.1 homozygous genotype in patients with oral squamous cell carcinoma.PMID 18951065Read ↗

MICA A5.1 homozygous genotype is associated with a risk for early-onset oral cancer.Semantic proximity Read ↗

Associations of high-resolution-typing-defined MICA and MICB polymorphisms, and the levels of soluble MICA and MICB with Oral Squamous Cell Carcinoma in Bulgarian patients.Semantic proximity Read ↗

An association between the MICA-A5.1 allele and an increased susceptibility to oral squamous cell carcinoma in Japanese patients.Semantic proximity Read ↗

Analysis of MUC6 polymorphisms on the clinicopathologic characteristics of Asian patients with oral squamous cell carcinoma.Semantic proximity Read ↗

The increase in the frequency of MICA gene A6 allele in oral squamous cell carcinoma.Semantic proximity Read ↗

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MICA polymorphism: biology and importance in immunity and disease.Semantic proximity Read ↗

Polymorphism of the MICA gene and risk for oral submucous fibrosis.Semantic proximity Read ↗

The Role of Non-classical and Chain-Related Human Leukocyte Antigen Polymorphisms in Laryngeal Squamous Cell CarcinomaSemantic proximity Read ↗

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.Semantic proximity Read ↗

Hepatitis B virus-induced hepatocellular carcinoma: functional roles of MICA variants.Semantic proximity Read ↗

Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.Semantic proximity Read ↗

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