Article
Relationship between soluble MICA and the MICA A5.1 homozygous genotype in patients with oral squamous cell carcinoma.
Clinical immunology (Orlando, Fla.) - 1 Mar 2009
Tamaki Shigehiro, Kawakami Masayoshi, Yamanaka Yasutsugu, Shimomura Hiroyuki, Imai Yuichiro, Ishida Jun-ichi, Yamamoto Kazuhiko, Ishitani Akiko, Hatake Katsuhiko, Kirita Tadaaki
Abstract excerpt
NK and cytotoxic T cells play an important role in the elimination of virus-infected and tumor cells through NKG2D activating receptors, which can promote the lysis of target cells by binding to the major histocompatibility complex class I-related chain A (MICA) proteins. Polymorphisms in MICA ma...
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