Article
Polymorphism of the MICA gene and risk for oral submucous fibrosis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jan 2004
Liu Chung-Ji, Lee Yann-Jinn, Chang Kuo-Wei, Shih Yi-Ning, Liu Hsin-Fu, Dang Ching-Wen
Abstract excerpt
BACKGROUND: Oral submucous fibrosis (OSF), an insidious, pre-cancerous, chronic disease that may affect the entire oral cavity and sometimes extend to the pharynx has been reported to be associated with immune function. The major histocompatibility complex (MHC) class I chain-related gene A (MICA) is expressed by keratinocytes and other epithelial cells, and its encoded protein interacts with gamma/delta T-cells...
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