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Article

Role of stromal tenascin-C in mouse prostatic development and epithelial cell differentiation.

Developmental biology - 15 Dec 2008

Ishii Kenichiro, Imanaka-Yoshida Kyoko, Yoshida Toshimichi, Sugimura Yoshiki

Abstract excerpt

Deregulation of epithelial-stromal interactions is considered to play a critical role in the initiation and promotion of benign prostatic hyperplasia (BPH) and prostate carcinoma (PCa). Expression of tenascin-C (TN-C), an extracellular matrix (ECM) glycoprotein, is reportedly higher in BPH and PCa as compared with normal prostate. Remodeling of the ECM alters the homeostatic balance between epithelium and stroma,...

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Source

Identifiers

PMID: 18950615
DOI: 10.1016/j.ydbio.2008.09.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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