Article
Tenascin-C in development and disease: gene regulation and cell function.
Matrix biology : journal of the International Society for Matrix Biology - 1 Dec 2000
Jones P L, Jones F S
Abstract excerpt
Tenascin-C (TN-C) is a modular and multifunctional extracellular matrix (ECM) glycoprotein that is exquisitely regulated during embryonic development and in adult tissue remodeling. TN-C gene transcription is controlled by intracellular signals that are generated by multiple soluble factors, integrins and mechanical forces. These external cues are interpreted by particular DNA control elements that interact with...
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