Conserved Gene Expression Programs Integrate Mammalian Prostate Development and Tumorigenesis

Abstract excerpt

Studies centered at the intersection of embryogenesis and carcinogenesis have identified striking parallels involving signaling pathways that modulate both developmental and neoplastic processes. In the prostate, reciprocal interactions between epithelium and stroma are known to influence neoplasia and also exert morphogenic effects via the urogenital sinus mesenchyme. In this study, we sought to determine...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Genetics and Reproduction
• Share to FOXO transcription factor regulation
• Share to Prostate Cancer Treatment and Research