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Article

Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160.

Journal of experimental & clinical cancer research : CR - 25 Oct 2008

Lu Yi, Yao Hang-Ping, Wang Ming-Hai

Abstract excerpt

The RON receptor tyrosine kinase regulates epithelial cell homeostasis and tumorigenesis by transducing multiple signals through its functional domains. The present study was to determine the significance of the entire C-terminus in RON or its variant RON160-mediated activities related to cell motility and tumorigenesis. Analysis of protein phosphorylation revealed that elimination of the entire C-terminus...

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Identifiers

PMID: 18950514
DOI: 10.1186/1756-9966-27-55
PMCID: PMC2584002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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