Article
Alterations in a defined extracellular region of the RON receptor tyrosine kinase promote RON-mediated motile and invasive phenotypes in epithelial cells.
International journal of oncology - 1 Jan 2010
Zhang Kun, Zhou Yong-Qing, Yao Hang-Ping, Wang Ming-Hai
Abstract excerpt
Cell migration followed by matrix invasion is a critical step required for epithelial cell differentiation, growth and survival. This study determined the RON receptor in regulation of motile-invasive phenotypes of epithelial cells. Two RON variants, RON165.e11p and RON165, with alterations in a...
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