Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOK-mediated signaling transductions.

Biochemical and biophysical research communications - 4 May 2007

Li Ying-Hua, Zhong Shan, Rong Zhi-Li, Ren Yong-Ming, Li Zhi-Yong, Zhang Shu-Ping, Chang Zhijie, Liu Li

Abstract excerpt

Receptor protein tyrosine kinases (RPTKs) are essential mediators of cell growth, differentiation, migration, and metabolism. Recently, a novel RPTK named NOK has been cloned and characterized. In current study, we investigated the role of the carboxyl terminal tyrosine 417 residue of NOK in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Mitogen-Activated Protein Kinases
Share to Oncogene Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Point Mutation

Share to Protein-Tyrosine Kinases

Share to Receptor Protein-Tyrosine Kinases

Share to STAT Transcription Factors

Share to Tyrosine

Source

Identifiers

PMID: 17367757
DOI: 10.1016/j.bbrc.2007.02.154

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17367757-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOK-mediated signaling transductions.PMID 17367757Read ↗

Cross-Talk between NOK and EGFR: Juxtamembrane and Kinase domain interactions enhancing STAT3/5 signaling in breast cancer tumorigenesisSemantic proximity Read ↗

NOK mediated mitogenic signaling is altered by P203L and V395I mutations.Semantic proximity Read ↗

EGFR signaling pathway occupies an important position in cancer‐related downstream signaling pathways of Pyk2Semantic proximity Read ↗

Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160.Semantic proximity Read ↗

FYN: emerging biological roles and potential therapeutic targets in cancerSemantic proximity Read ↗

Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future ResearchSemantic proximity Read ↗

Differential tyrosine phosphorylation controls the function of CNK1 as a molecular switch in signal transduction.Semantic proximity Read ↗

All Good Things Must End: Termination of Receptor Tyrosine Kinase Signal.Semantic proximity Read ↗

GALNT1 drives aggressive phenotypes of rheumatoid synoviocytes via NEK9 O-glycosylation.Semantic proximity Read ↗

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survivalSemantic proximity Read ↗

Autoinhibitory mechanisms in receptor tyrosine kinases.Semantic proximity Read ↗

Effects of ERK1/2 S-nitrosylation on ERK1/2 phosphorylation and cell survival in glioma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.