Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p.

The Journal of cell biology - 13 Oct 2014

Liu Dongmei, Novick Peter

Abstract excerpt

The exocyst serves to tether secretory vesicles to cortical sites specified by polarity determinants, in preparation for fusion with the plasma membrane. Although most exocyst components are brought to these sites by riding on secretory vesicles as they are actively transported along actin cables...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Cyclin-Dependent Kinases
Share to GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to Phosphatidylinositol 4,5-Diphosphate

Share to rho GTP-Binding Proteins

Share to Secretory Vesicles

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25313406
DOI: 10.1083/jcb.201404122
PMCID: PMC4195821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25313406-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p.PMID 25313406Read ↗

An internal domain of Exo70p is required for actin-independent localization and mediates assembly of specific exocyst components.Semantic proximity Read ↗

Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane.Semantic proximity Read ↗

Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth.Semantic proximity Read ↗

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex.Semantic proximity Read ↗

The Rho GTPase Rho3 has a direct role in exocytosis that is distinct from its role in actin polarity.Semantic proximity Read ↗

Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth.Semantic proximity Read ↗

Exocyst Requirement for Endocytic Traffic Directed Toward the Apical and Basolateral Poles of Polarized MDCK CellsSemantic proximity Read ↗

Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis.Semantic proximity Read ↗

Phosphatidylinositol 4,5-bisphosphate mediates the targeting of the exocyst to the plasma membrane for exocytosis in mammalian cells.Semantic proximity Read ↗

Polarized Exocytosis Induces Compensatory Endocytosis by Sec4p-Regulated Cortical Actin Polymerization.Semantic proximity Read ↗

Cdc42 interacts with the exocyst and regulates polarized secretion.Semantic proximity Read ↗

The Physcomitrella patens exocyst subunit EXO70.3d has distinct roles in growth and development, and is essential for completion of the moss life cycle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.