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Article

Two single nucleotide polymorphisms in PRDM9 (MEISETZ) gene may be a genetic risk factor for Japanese patients with azoospermia by meiotic arrest.

Journal of assisted reproduction and genetics - 1 Jan 2000

Miyamoto Toshinobu, Koh Eitetsu, Sakugawa Naoko, Sato Hisashi, Hayashi Hiroaki, Namiki Mikio, Sengoku Kazuo

Abstract excerpt

PURPOSE: To investigate whether defects in human PRDM9, CDK2 and PSMC3IP are associated with azoospermia Mutational analysis was performed in Japanese patients with azoospermia caused by meiotic arrest. METHODS: Mutational screening of the coding regions of human PRDM9, CDK2 and PSMC3IP was done by direct sequencing using genomic DNA from 18 Japanese patients. Statistical analysis of the detected coding single...

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Source

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Identifiers

PMID: 18941885
DOI: 10.1007/s10815-008-9270-x
PMCID: PMC2593767

Genes

PRDM9
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two single nucleotide polymorphisms in PRDM9 (MEISETZ) gene may be a genetic risk factor for Japanese patients with azoospermia by meiotic arrest.PMID 18941885Read ↗

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