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Article

Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia.

Journal of andrology - 1 Jan 2000

Irie Shinji, Tsujimura Akira, Miyagawa Yasushi, Ueda Tomohiro, Matsuoka Yasuhiro, Matsui Yasuhisa, Okuyama Akihiko, Nishimune Yoshitake, Tanaka Hiromitsu

Abstract excerpt

To investigate the possible association between variations in the PRDM9 (MEISETZ) gene and impaired spermatogenesis in humans, we screened for mutations in the human PRDM9 gene using DNA from 217 sterile male patients and 162 proven fertile male volunteers. Two single-nucleotide polymorphisms (SNPs), 17353G>T (Gly433Val) and 18109C>G (Thr685Arg), were identified, as well as an intronic SNP, 15549G>T. These SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histone-Lysine N-Methyltransferase

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Source

Identifiers

PMID: 19168450
DOI: 10.2164/jandrol.108.006262

Genes

PRDM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia.PMID 19168450Read ↗

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