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Article

Multiple sclerosis in families: risk factors beyond known genetic polymorphisms.

Neurogenetics - 1 Apr 2016

Akkad Denis A, Lee De-Hyung, Bruch Kathrin, Haghikia Aiden, Epplen Jörg T, Hoffjan Sabine, Linker Ralf A

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system that predominantly affects young adults. The genetic contributions to this multifactorial disease were underscored by genome wide association studies and independent replication studies. A weighted genetic risk score (wGRS) was recently established using the identified MS risk loci in order to predict MS outcome...

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PMID: 26865406
DOI: 10.1007/s10048-016-0474-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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