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Article

Mir-144 selectively regulates embryonic α-hemoglobin synthesis during primitive erythropoiesis

21 Oct 2008

Abstract excerpt

Precise transcriptional control of developmental stage-specific expression and switching of alpha- and beta-globin genes is significantly important to understand the general principles controlling gene expression and the pathogenesis of thalassemia. Although transcription factors regulating beta-globin genes have been identified, little is known about the microRNAs and trans-acting mechanism controlling...

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Share to Epigenetics and DNA Methylation
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PMID: 18941117
DOI: 10.1182/blood-2008-08-174854

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