Article
Mutations in Drosophila myb lead to centrosome amplification and genomic instability.
Development (Cambridge, England) - 1 Jan 2002
Fung Siau-Min, Ramsay Gary, Katzen Alisa L
Abstract excerpt
We have previously established that the single myb gene in Drosophila melanogaster, Dm myb, which is related to the proto-oncogene Myb, is required for the G2/M transition of the cell cycle and for suppression of endoreduplication in pupal wing cells. We now report that studies of the abdominal phenotype in loss-of-function Dm myb mutants reveal additional roles for Dm myb in the cell cycle, specifically in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
