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Article

Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.

Metabolism: clinical and experimental - 1 Nov 2008

Folsom Aaron R, Peacock James M, Demerath Ellen, Boerwinkle Eric

Abstract excerpt

An E40K loss-of-function variant in the ANGPTL4 gene is associated with substantially reduced plasma triglyceride levels in white persons, but its association with cardiovascular disease occurrence has not been reported. The prospective, population-based Atherosclerosis Risk in Communities Study measured the E40K ANGPTL4 variant in approximately 10000 white participants and determined its association with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18940399
DOI: 10.1016/j.metabol.2008.06.016
PMCID: PMC2707767

Genes

ANGPTL4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.PMID 18940399Read ↗

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Impact of loss-of-function in angiopoietin-like 4 on the human phenomeSemantic proximity Read ↗

Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study.Semantic proximity Read ↗

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