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Article

De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes.

Genesis (New York, N.Y. : 2000) - 1 Dec 2008

Chiba Hatsune, Hirasawa Ryutaro, Kaneda Masahiro, Amakawa Yuko, Li En, Sado Takashi, Sasaki Hiroyuki

Abstract excerpt

In female mouse embryos, the paternal X chromosome (Xp) is preferentially inactivated during preimplantation development and trophoblast differentiation. This imprinted X-chromosome inactivation (XCI) is partly due to an activating imprint on the maternal X chromosome (Xm), which is set during oocyte growth. However, the nature of this imprint is unknown. DNA methylation is one candidate, and therefore we...

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PMID: 18932249
DOI: 10.1002/dvg.20438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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