Article
Association of mitochondrial haplogroup J and mtDNA oxidative damage in two different North Spain elderly populations.
Biogerontology - 1 Aug 2009
Domínguez-Garrido Elena, Martínez-Redondo Diana, Martín-Ruiz Carmen, Gómez-Durán Aurora, Ruiz-Pesini Eduardo, Madero Pilar, Tamparillas Manuel, Montoya Julio, von Zglinicki Thomas, Díez-Sánchez Carmen, López-Pérez Manuel J
Abstract excerpt
This work investigates the association between longevity, mitochondrial DNA (mtDNA) variants and oxidative DNA damage in an older than 85 years population. The participants, similar in genetic and cultural background as well as gender distribution, come from villages near to the Pyrenees Mountains (900-1,400 m altitude) (n = 69) and the Ebro's Valley (200-300 m altitude) (n = 69) in Spain. Our results show an...
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