Article
Association of mitochondrial DNA haplogroups with exceptional longevity in a Chinese population.
PloS one - 29 Jul 2009
Cai Xiao-yun, Wang Xiao-feng, Li Shi-lin, Qian Ji, Qian De-gui, Chen Fei, Yang Ya-jun, Yuan Zi-yu, Xu Jun, Bai Yidong, Yu Shun-zhang, Jin Li
Abstract excerpt
BACKGROUND: Longevity is a multifactorial trait with a genetic contribution, and mitochondrial DNA (mtDNA) polymorphisms were found to be involved in the phenomenon of longevity. METHODOLOGY/PRINCIPAL FINDINGS: To explore the effects of mtDNA haplogroups on the prevalence of extreme longevity (EL), a population based case-control study was conducted in Rugao--a prefecture city in Jiangsu, China. Case subjects...
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